Alzheimer’s Disease: Diagnosis and MRI Imaging

نویسندگان

  • Margaret D. Phillips
  • Stephen J. Pomeranz
چکیده

17. Verwey NA, van der Flier WM, et al. “A worldwide multicentre comparison of assays for cerebral spinal fluid biomarkers in Alzheimer’s disease.” Ann Clin Biochem 209; 26:235-40 (E-published Apr. 2, 2009). Conclusion: While no single finding affords the diagnosis of Alzheimer’s disease, the brain MRI pattern of atrophy in the mesial and lateral temporal, isthmus cingulate, and orbitofrontal areas provides 83% sensitivity and 93% specificity. In Alzheimer’s, CSF amyloid is decreased, while tau is increased. Pursuit of suitable blood markers continues. ■

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تاریخ انتشار 2009